abstract：BACKGROUND:Previous studies suggested that apolipoprotein A5 (ApoA5) genetic polymorphisms (SNPs) may result in lipid metabolism disorders. Therefore, genetic polymorphisms in ApoA5 may be associated with the occurrence of osteonecrosis of femoral head (ONFH). METHODS:We designed a case-control study including 223 pat...

journal_title：Diagnostic pathology

authors： Cui Y,Kaisaierjiang A,Cao P,Wu ZY,Lv Q

更新日期：2014-12-17 00:00:00

abstract：BACKGROUND:We report a case of a 33-year-old man who presented with immunoglobulin (Ig)G4-related disease (IgG4-RD) forming a pseudotumor in the left paratesticular region during oral administration of corticosteroid for Wells syndrome, which involves cellulitis with eosinophilia. CASE PRESENTATION:The patient was int...

journal_title：Diagnostic pathology

authors： Karashima T,Taniguchi Y,Shimamoto T,Nao T,Nishikawa H,Fukata S,Kamada M,Inoue K,Oko K,Nakajima H,Sano S,Matsumoto M,Kuroda N,Kamei Y,Shuin T

更新日期：2014-12-09 00:00:00

abstract：BACKGROUND:The histopathological subtype, nuclear grade and presence or absence of comedonecrosis are established as critical elements in the reporting of ductal carcinoma in situ (DCIS) of the breast. The aims of this study were to determine the frequencies of morphological subtypes of DCIS, nuclear grade and comedone...

journal_title：Diagnostic pathology

authors： Perez AA,Balabram D,Salles Mde A,Gobbi H

更新日期：2014-12-03 00:00:00

abstract：BACKGROUND:The association between the Val158Met polymorphism in the catechol-O-methyltransferase (COMT) gene and lung cancer risk remains controversial and inconclusive. Therefore, the meta-analysis was performed to provide a quality reevaluation of the association between the COMT Val158Met polymorphism and the risk ...

journal_title：Diagnostic pathology

authors： Tan X,Chen M

更新日期：2014-10-04 00:00:00

abstract：BACKGROUND:To identify critical genes and biological pathways in acute lung injury (ALI), a comparative analysis of gene expression profiles of patients with ALI + sepsis compared with patients with sepsis alone were performed with bioinformatic tools. METHODS:GSE10474 was downloaded from Gene Expression Omnibus, incl...

journal_title：Diagnostic pathology

authors： Guo Z,Zhao C,Wang Z

更新日期：2014-09-26 00:00:00

abstract：UNLABELLED:Perivascular epithelioid cell tumors (PEComas) encompass a group of rare mesenchymal neoplasms, which typically have a perivascular location with dual melanocytic and muscular differentiation. They are found in a variety of localizations, though lesions in the liver are exceedingly rare. Because of their rar...

journal_title：Diagnostic pathology

authors： Ameurtesse H,Chbani L,Bennani A,Toughrai I,Beggui N,Kamaoui I,Elfatemi H,Harmouch T,Amarti A

更新日期：2014-07-17 00:00:00

abstract：BACKGROUND:Morphine has been widely used as a clinical anesthetic and analgesic. However, abuse of morphine might result in psychological and physiological dependence. Previous studies have indicated that memory mechanisms play critical roles in morphine dependence. METHODS:Morphine dependence was established in mice ...

journal_title：Diagnostic pathology

authors： Ye J,Yang Z,Li C,Cai M,Zhou D,Zhang Q,Wei Y,Wang T,Liu Y

更新日期：2014-07-10 00:00:00

abstract：BACKGROUND:Preventive and therapeutic options for renal failure are still limited. Gene expression profile analysis is powerful in the identification of biological differences between end stage renal failure patients and healthy controls. Previous studies mainly used variance/regression analysis without considering var...

journal_title：Diagnostic pathology

authors： Ding S,Xu Y,Hao T,Ma P

更新日期：2014-07-05 00:00:00

abstract：BACKGROUND:A number of studies have examined the association between interleukin-6 (IL-6) rs1800796 polymorphism and risk of lung cancer but revealed inconsistent results. The aim of this study was to clarify the association between IL-6 rs1800796 polymorphism and risk of lung cancer. METHODS:Literature databases incl...

journal_title：Diagnostic pathology

authors： Wang W,Chen J,Zhao F,Zhang B,Yu H

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Metastatic spread of tumor through lymphatic vasculature is an important adverse prognostic factor in a variety of human cancer and tumor lymphangiogenesis requires the interplay of several growth factors. Platelet-derived growth factor (PDGF)-BB and vascular endothelial growth factor (VEGF)-C are two import...

journal_title：Diagnostic pathology

authors： Liu J,Liu C,Qiu L,Li J,Zhang P,Sun Y

更新日期：2014-06-27 00:00:00

abstract：BACKGROUND:Ki67 is currently the proliferation biomarker of choice, with both prognostic and predictive value in breast cancer. A lack of consensus regarding Ki67 use in pre-analytical, analytical and post-analytical practice may hinder its formal acceptance in the clinical setting. METHODS:One hundred breast cancer s...

journal_title：Diagnostic pathology

authors： Romero Q,Bendahl PO,Fernö M,Grabau D,Borgquist S

更新日期：2014-06-16 00:00:00

abstract：BACKGROUND:Reduced DNA repair capacities due to inherited polymorphisms may increase the susceptibility to cancers including gastric cancer. Previous studies investigating the association between Xeroderma Pigmentosum group C (XPC) gene polymorphisms and gastric cancer risk reported inconsistent results. We performed a...

journal_title：Diagnostic pathology

authors： Peng Q,Chen Z,Lu Y,Lao X,Mo C,Li R,Qin X,Li S

更新日期：2014-05-23 00:00:00

abstract：BACKGROUND:The aim of this report is related to adult primary paratesticular mesenchymal tumors with emphasis on a case presentation and discussion of the spermatic cord leiomyosarcoma. Primary paratesticular tumors are rare, only accounting for 7% to 10% of all intrascrotal tumors. In adults, more than 75% of these le...

journal_title：Diagnostic pathology

authors： Galosi AB,Scarpelli M,Mazzucchelli R,Lopez-Beltran A,Giustini L,Cheng L,Montironi R

更新日期：2014-05-06 00:00:00

abstract：BACKGROUND:The optimal course of clinical follow-up after a diagnosis of breast papillary lesion on a core needle biopsy (CNB) remains elusive. In particular, no reports in literature have addressed this question in African-American population. We describe our experience with breast papillary lesions in a primarily Afr...

journal_title：Diagnostic pathology

authors： Wang H,Tsang P,D'Cruz C,Clarke K

更新日期：2014-04-24 00:00:00

abstract：BACKGROUND:70-80% of sporadic endometrial carcinomas are defined as endometrioid carcinoma (EC). Early-stage, well differentiated endometrial carcinomas usually retain expression of estrogen and progesterone receptors (ER and PR, respectively), as advanced stage, poorly differentiated tumors often lack one or both of t...

journal_title：Diagnostic pathology

authors： Kreizman-Shefer H,Pricop J,Goldman S,Elmalah I,Shalev E

更新日期：2014-03-31 00:00:00

abstract：UNLABELLED:Cat scratch disease, necrotizing granulomatous lymphadenitis caused by Bartonella henselae, usually benign and self-limited. However, various clinical manifestations and no pathognomonic histopathologic features can lead to misinterpretations and diagnostic disputes. We report a case of cat scratch disease i...

journal_title：Diagnostic pathology

authors： Shin OR,Kim YR,Ban TH,Lim T,Han TH,Kim SY,Seo KJ

更新日期：2014-03-19 00:00:00

abstract：PURPOSE:Patellofemoral pathology is common, and patellofemoral dislocation mainly affects adolescents and young adults. We conducted a meta-analysis exclusively of RCTs to compare the clinical outcomes of patellar dislocation patients managed operatively versus non-operatively. METHODS:After systematic review of elect...

journal_title：Diagnostic pathology

authors： Cheng B,Wu X,Ge H,Qing Sun Y,Zhang Q

更新日期：2014-03-18 00:00:00

abstract：BACKGROUND:Colorectal cancer (CRC) remains a major worldwide cause of cancer-related morbidity and mortality largely due to the insidious onset of the disease. The current clinical procedures utilized for disease diagnosis are invasive, unpleasant, and inconvenient. Hence, the need for simple blood tests that could be ...

journal_title：Diagnostic pathology

authors： Fan NJ,Kang R,Ge XY,Li M,Liu Y,Chen HM,Gao CF

更新日期：2014-03-12 00:00:00

abstract：UNLABELLED:Gastroenteropancreatic neuroendocrine tumors are the most incident neuroendocrine tumors. In the new WHO classification (2010) the embryological derivation of each neoplastic entity is one of the most important parameters. Gangliocytic Paraganglioma is a tumor originating in the hindgut, a rare neoplasm, gen...

journal_title：Diagnostic pathology

authors： Tatangelo F,Cantile M,Pelella A,Losito NS,Scognamiglio G,Bianco F,Belli A,Botti G

更新日期：2014-03-12 00:00:00

abstract：BACKGROUND:Prostate cancer patients with rectal involvement are rare, and the factors associated with the survival of these patients are yet to be elucidated. PATIENTS AND METHODS:We collected data on patients who were admitted to our hospital for prostate cancer in the last thirteen years and of those in studies in t...

journal_title：Diagnostic pathology

authors： Wang H,Yao Y,Li B

更新日期：2014-02-20 00:00:00

abstract：UNLABELLED:As rare condition, mucoepidermoid carcinoma may occur in liver although its etiology and pathogenesis is still unclear. We report here a case of intrahepatic mucoepidermoid carcinoma misdiagnosed as cholangiocarcinoma and squamous cell carcinoma by preoperative radiologic and intraoperative histological exam...

journal_title：Diagnostic pathology

authors： Guo XQ,Li B,Li Y,Tian XY,Li Z

更新日期：2014-01-29 00:00:00

abstract：OBJECTIVES:RAD51 gene plays an important role in the pathogenesis of squamous cell carcinoma of the head and neck (SCCHN), colorectal cancer, ovarian cancer and acute leukaemia. A number of studies assessed the association between RAD51 135G/C polymorphism and the risk of these cancers in different population. However,...

journal_title：Diagnostic pathology

authors： Cheng D,Shi H,Zhang K,Yi L,Zhen G

更新日期：2014-01-23 00:00:00

abstract：BACKGROUND:To investigate the therapeutic effect of p38-MAPK inhibitor, SB203580, on dry eye in a mouse model of Sjögren's syndrome (MRL/lpr mice). METHODS:18 female BALB/c mice and 44 female MRL/lpr mice were included. Mice were randomly assigned to the control or treatment group. The expression of phospho-p38 MAPK i...

journal_title：Diagnostic pathology

authors： Ma X,Zou J,He L,Zhang Y

更新日期：2014-01-20 00:00:00

abstract：BACKGROUND:To quantify the effect of cruciferous vegetable consumption on the incidence of ovarian cancer by meta-analyzing the existing observational studies and provides quantitative and high-level evidence. METHODS:A detailed literature search of Medline and EMBASE for all relevant papers published. A meta-analysis...

journal_title：Diagnostic pathology

authors： Han B,Li X,Yu T

更新日期：2014-01-20 00:00:00

abstract：UNLABELLED:Cutaneous mast cell tumours (MCTs) are the most common skin tumours in dogs. Due to the prevalence of canine MCTs and the variable biologic behavior of this disease, accurate prognostication and a thorough understanding of MCT biology are critical for the treatment of this disease. A cytologic diagnosis of m...

journal_title：Diagnostic pathology

authors： Hosseini E,Pedram B,Bahrami AM,Moghaddam MH,Javanbakht J,Ghomi FE,Moghaddam NJ,Koohestani M,Shafiee R

更新日期：2014-01-20 00:00:00

abstract：BACKGROUND:The Eastern Quebec Telepathology Network (called Réseau de Télépathologie de l'Est du Québec in French) was created to provide uniform diagnostic telepathology services in a huge territory with low population density. We report our first 3-year experience. METHODS:The network was funded equally by the Québe...

journal_title：Diagnostic pathology

authors： Têtu B,Perron É,Louahlia S,Paré G,Trudel MC,Meyer J

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Crowdsourcing, i.e., the outsourcing of tasks typically performed by a few experts to a large crowd as an open call, has been shown to be reasonably effective in many cases, like Wikipedia, the Chess match of Kasparov against the world in 1999, and several others. The aim of the present paper is to describe ...

journal_title：Diagnostic pathology

authors： Della Mea V,Maddalena E,Mizzaro S,Machin P,Beltrami CA

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Human papillomavirus-associated oropharyngeal carcinoma (HPV-OPC) is clinicopathologically distinct entity from the HPV-unassociated one (nHPV-OPC). This study aimed to determine the relationship between histological subtypes of OPC and HPV status for Japanese cases and to identify histological structures of...

journal_title：Diagnostic pathology

authors： Fujimaki M,Fukumura Y,Mitani K,Kurisaki A,Yokoyama J,Ikeda K,Yao T

更新日期：2013-12-19 00:00:00

abstract：:Endometriosis is a clinical entity characterized by the presence of normal endometrial mucosa abnormally implanted in locations other than the uterine cavity. Endometriosis can be either endopelvic or extrapelvic depending on the location of endometrial tissue implantation. Despite the rarity of extrapelvic endometrio...

journal_title：Diagnostic pathology

authors： Machairiotis N,Stylianaki A,Dryllis G,Zarogoulidis P,Kouroutou P,Tsiamis N,Katsikogiannis N,Sarika E,Courcoutsakis N,Tsiouda T,Gschwendtner A,Zarogoulidis K,Sakkas L,Baliaka A,Machairiotis C

更新日期：2013-12-02 00:00:00

abstract：:A 42-year-old male presented right upper abdomen pain for more than 6 days, which misdiagnose calculus of intrahepatic duct and acute cholecystitis. An approximately 1.5 cm x 1.0 cm x 1.0 cm nodule was found and resected in left lateral lobe of hepatic. Pathological examination showed spindle cell and fibroblast -like...

journal_title：Diagnostic pathology

authors： Liu Q,Liu J,Chen W,Mao S,Guo Y

更新日期：2013-12-02 00:00:00

abstract：BACKGROUND:High altitude pulmonary edema (HAPE) affects individuals and is characterized by alveolar flooding with protein-rich edema as a consequence of blood-gas barrier disruption. In this study, we hypothesized that aquaporin 5 (AQP5) which is one kind of water channels may play a role in preservation of alveolar e...

journal_title：Diagnostic pathology

authors： She J,Bi J,Tong L,Song Y,Bai C

更新日期：2013-11-25 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate how differences in expression of HER2 between primary gastric cancers (PGCs) and their corresponding metastatic lymph nodes (LMNs) might affect its potential as a prognostic indicator in treatments including anti-HER2 agents. METHODS:The analysis was conducted in 102...

journal_title：Diagnostic pathology

authors： Kochi M,Fujii M,Masuda S,Kanamori N,Mihara Y,Funada T,Tamegai H,Watanabe M,Suda H,Takayama T

更新日期：2013-11-21 00:00:00

abstract：UNLABELLED:We report a case of recurrent cutaneous necrotizing eosinophilic vasculitis (RCNEV) in a 57-year-old male. The patient presented with papules and pruritus of the lower limbs of more than 1 month duration, and with angioedema and intensively pruritic, necrotizing lesions of the bilateral anterior tibias and f...

journal_title：Diagnostic pathology

authors： Li W,Cao W,Song H,Ciu Y,Lu X,Zhang F

更新日期：2013-11-07 00:00:00

abstract：UNLABELLED:A 34-year-old female, with a history of continued asbestos exposure, presented with a papillary peritoneal mesothelioma with a diffuse, prominent clear foamy cell change, with microvacuolation in its papillary lining, that expressed cytokeratins 7, 5/6 and calretinin as well as nuclear WT-1 and apical membra...

journal_title：Diagnostic pathology

authors： Stolnicu S,Quiñonez E,Boros M,Molnar C,Dulcey I,Nogales FF

更新日期：2013-09-25 00:00:00

abstract：UNLABELLED:Imaging appearance of cyst-like changes is most frequently described in primary neuroendocrine lesions, especially pancreatic NETs.The imaging finding of a pseudocystic lesion of the liver puts in differential diagnosis many pathologies such as infectious diseases, simple biliary cysts up to biliary cystaden...

journal_title：Diagnostic pathology

authors： Fiori S,Del Gobbo A,Gaudioso G,Caccamo L,Massironi S,Cavalcoli F,Bosari S,Ferrero S

更新日期：2013-09-13 00:00:00

abstract：UNLABELLED:Since first reported in 1986, 14 cases of extrauterine adenomyoma have been reported in the English literature, most often occurring in the ovaries. In this report, we present the first case of extrauterine adenomyoma involving the liver in a 29-year-old woman who presented with a 2-year history of low back ...

journal_title：Diagnostic pathology

authors： Huanwen W,Hui Z,Xiaowei X,Zhaohui L

更新日期：2013-08-05 00:00:00

abstract：BACKGROUND:The novel pandemic A (H1N1) pdm09 virus was first identified in Mexico in April 2009 and since then it spread worldwide over a short period of time. Although the virus infection is generally associated with mild disease and a relatively low mortality, it is projected that mutations in specific regions of the...

journal_title：Diagnostic pathology

authors： Moussi AE,Kacem MA,Pozo F,Ledesma J,Cuevas MT,Casas I,Slim A

更新日期：2013-07-31 00:00:00

abstract：BACKGROUND:Kombucha, a fermented tea (KT) is claimed to possess many beneficial properties. The aim of this study was to evaluate clinical and histopathological alterations of Kombucha tea and Nitrofurazone on cutaneous full-thickness wounds healing in rat. METHODS:In present study 24 Wister -albino rats weighing 150-...

journal_title：Diagnostic pathology

authors： Barati F,Javanbakht J,Adib-Hashemi F,Hosseini E,Safaeie R,Rajabian M,Razmjoo M,Sedaghat R,Aghamohammad Hassan M

更新日期：2013-07-17 00:00:00

abstract：BACKGROUND:The polymorphism Pro12Ala in peroxisome proliferator-activated receptor-γ2 gene (PPARγ2) has been reported to be associated with diabetic nephropathy (DN) in some studies, though the results remain inconclusive. To explore this relationship between PPARγ2 Pro12Ala polymorphism and the susceptibility for DN, ...

journal_title：Diagnostic pathology

authors： Wang L,Teng Z,Cai S,Wang D,Zhao X,Yu K

更新日期：2013-07-15 00:00:00

abstract：BACKGROUND:This study is to investigate the expression of progranulin (PGRN) in systemic lupus erythematosus (SLE) patients and the effect of glucocorticoid (GC) treatment on its expression. METHODS:Thirty newly diagnosed severe SLE patients and 30 healthy subjects were enrolled in this study. The serum levels of PGRN...

journal_title：Diagnostic pathology

authors： Qiu F,Song L,Ding F,Liu H,Shu Q,Yang N,Liu W,Li X

更新日期：2013-05-23 00:00:00